BDBM50248535 2-(methylamino)-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide::5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-2-(methylamino)-N-(4-methylthiazol-2-yl)benzamide::CHEMBL490961

SMILES Cc1csc(n1)NC(=O)c2cc(ccc2NC)Sc3nncn3C

InChI Key InChIKey=XRJAKERBMMBUGR-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248535   

TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50248535(5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-2-(methylam...)
Affinity DataEC50:  1.10E+3nMAssay Description:Activation of human glucokinase by glucose-6-phosphate dehydrogenase coupled continuous spectrophotometric assay in presence of 2.5 mM glucoseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50248535(5-(4-methyl-4H-1,2,4-triazol-3-ylthio)-2-(methylam...)
Affinity DataEC50:  330nMAssay Description:Activation of human glucokinase by glucose-6-phosphate dehydrogenase coupled continuous spectrophotometric assay in presence of 10 mM glucoseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)