BDBM50248447 3-(1-methyl-4-(quinolin-6-yloxy)-1H-indol-3-yl)-N-(2,4,5-trifluorophenylsulfonyl)acrylamide::CHEMBL523608

SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc4ncccc4c3)cccc12

InChI Key InChIKey=JCPAJFRCLCWAKW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248447   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248447(3-(1-methyl-4-(quinolin-6-yloxy)-1H-indol-3-yl)-N-...)
Affinity DataIC50: 8.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248447(3-(1-methyl-4-(quinolin-6-yloxy)-1H-indol-3-yl)-N-...)
Affinity DataIC50: 168nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed