BDBM50248426 (R)-4-((1-(4-(2-methyl-4-(2-(pyridin-4-yl)ethyl)piperazin-1-ylsulfonyl)phenyl)cyclopropyl)methyl)morpholine::CHEMBL489707

SMILES C[C@@H]1CN(CCc2ccncc2)CCN1S(=O)(=O)c1ccc(cc1)C1(CN2CCOCC2)CC1

InChI Key InChIKey=ZCTFCIROSWFYBV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248426   

LigandPNGBDBM50248426((R)-4-((1-(4-(2-methyl-4-(2-(pyridin-4-yl)ethyl)pi...)
Affinity DataIC50: 505nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248426((R)-4-((1-(4-(2-methyl-4-(2-(pyridin-4-yl)ethyl)pi...)
Affinity DataIC50: 8nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed