BDBM50248393 3-(4-(4-chloro-2-fluorophenoxy)-1-methyl-1H-indol-3-yl)-N-(2,4,5-trifluorophenylsulfonyl)acrylamide::CHEMBL490896

SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)cc3F)cccc12

InChI Key InChIKey=MNDBWMVLUHQMEA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248393   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248393(3-(4-(4-chloro-2-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50: 4.40nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248393(3-(4-(4-chloro-2-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50: 156nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed