BDBM50248382 (+/-)-1-Oxo-hexahydro-1lambda*4*-thiopyran-4-carboxylic acid{(S)-3-[4-(3-isopropyl-5-methyl-[1,2,4]triazol-4-yl)-piperidin-1-yl]-1-phenyl-butyl}-amide::CHEMBL523267

SMILES CC(C)c1nnc(C)n1C1CCN(CC1)C(C)C[C@H](NC(=O)C1CCS(=O)CC1)c1ccccc1

InChI Key InChIKey=LEHOUXIHBMZBJZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248382   

TargetC-C chemokine receptor type 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248382((+/-)-1-Oxo-hexahydro-1lambda*4*-thiopyran-4-carbo...)
Affinity DataIC50: 4.87nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed