BDBM50248350 CHEMBL514941::N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-N2-methylquinazoline-2,4-diamine

SMILES CNc1nc(Nc2ccc(cc2)-c2nc3ccccc3s2)c2cc(OC)c(OC)cc2n1

InChI Key InChIKey=JMAGQLOPVXHYBU-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50248350   

TargetAurora kinase B(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50248350(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora B by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50248350(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-...)
Affinity DataIC50: 630nMAssay Description:Inhibition of insulin receptor by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50248350(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EphB4 by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50248350(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TIE2 by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248350(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR2 by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248350(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGF1R by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50248350(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248350(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Src by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50248350(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora A by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed