BDBM50248349 CHEMBL473553::N-(4-(benzo[d]thiazol-2-yl)-3-methoxyphenyl)-6,7-dimethoxyquinazolin-4-amine

SMILES COc1cc2ncnc(Nc3ccc(-c4nc5ccccc5s4)c(OC)c3)c2cc1OC

InChI Key InChIKey=CBIHKNQEUSGCEN-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50248349   

TargetAurora kinase B(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50248349(N-(4-(benzo[d]thiazol-2-yl)-3-methoxyphenyl)-6,7-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora B by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50248349(N-(4-(benzo[d]thiazol-2-yl)-3-methoxyphenyl)-6,7-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of insulin receptor by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248349(N-(4-(benzo[d]thiazol-2-yl)-3-methoxyphenyl)-6,7-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGF1R by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50248349(N-(4-(benzo[d]thiazol-2-yl)-3-methoxyphenyl)-6,7-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EphB4 by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248349(N-(4-(benzo[d]thiazol-2-yl)-3-methoxyphenyl)-6,7-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR2 by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248349(N-(4-(benzo[d]thiazol-2-yl)-3-methoxyphenyl)-6,7-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Src by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50248349(N-(4-(benzo[d]thiazol-2-yl)-3-methoxyphenyl)-6,7-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora A by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50248349(N-(4-(benzo[d]thiazol-2-yl)-3-methoxyphenyl)-6,7-d...)
Affinity DataIC50: 63nMAssay Description:Inhibition of EGFR by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed