BDBM50248333 3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-3-yl)-N-(2,4,5-trifluorophenylsulfonyl)acrylamide::CHEMBL472754

SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(F)c(Cl)c3)cccc12

InChI Key InChIKey=XYBBIVJFBMLOCH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50248333   

TargetProstaglandin E2 receptor EP1 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248333(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radioligand from EP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248333(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radioligand from EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248333(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radioligand from EP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248333(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50: 3.16E+3nMAssay Description:Displacement of radioligand from FP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248333(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50: 9.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248333(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50: 61.1nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed