BDBM50248309 (R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(2-(pyridin-4-yl)ethyl)piperazine::CHEMBL515876

SMILES C[C@@H]1CN(CCc2ccncc2)CCN1S(=O)(=O)c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=KCQXBMXXGBBPNC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248309   

LigandPNGBDBM50248309((R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(2-(...)
Affinity DataIC50: 61nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248309((R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(2-(...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed