BDBM50248308 (2R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(1-(pyridin-4-yl)ethyl)piperazine::CHEMBL473350

SMILES CC(N1CCN([C@H](C)C1)S(=O)(=O)c1ccc(cc1)C(C)(C)C)c1ccncc1

InChI Key InChIKey=DITLQKIQKDAIBV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248308   

LigandPNGBDBM50248308((2R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(1-...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248308((2R)-1-(4-tert-butylphenylsulfonyl)-2-methyl-4-(1-...)
Affinity DataIC50: 96nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed