BDBM50248307 (R)-1-(4-(2-fluoropropan-2-yl)phenylsulfonyl)-2-methyl-4-(2-(pyridin-4-yl)ethyl)piperazine::CHEMBL473349

SMILES C[C@@H]1CN(CCc2ccncc2)CCN1S(=O)(=O)c1ccc(cc1)C(C)(C)F

InChI Key InChIKey=VDLINOGFWKLZFK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248307   

LigandPNGBDBM50248307((R)-1-(4-(2-fluoropropan-2-yl)phenylsulfonyl)-2-me...)
Affinity DataIC50: 36nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed