BDBM50248278 3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)-N-(2,4,5-trifluorophenylsulfonyl)acrylamide::CHEMBL475349

SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc(Cl)cc3Cl)cccc12

InChI Key InChIKey=QSJCTMZUCQMDLT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50248278   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248278(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)
Affinity DataIC50: 9.30E+3nMAssay Description:Displacement of radioligand from EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248278(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radioligand from EP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248278(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)
Affinity DataIC50: 3.57E+3nMAssay Description:Displacement of radioligand from FP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248278(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)
Affinity DataIC50: 3.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248278(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)
Affinity DataIC50: 16.7nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed