BDBM50248276 CHEMBL516394::N-(3,4-difluorophenylsulfonyl)-3-(1-methyl-4-(quinoxalin-2-yloxy)-1H-indol-3-yl)acrylamide

SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3cnc4ccccc4n3)cccc12

InChI Key InChIKey=HEQDAOHOZKIVIX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248276   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248276(N-(3,4-difluorophenylsulfonyl)-3-(1-methyl-4-(quin...)
Affinity DataIC50: 6.10nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248276(N-(3,4-difluorophenylsulfonyl)-3-(1-methyl-4-(quin...)
Affinity DataIC50: 217nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed