BDBM50248171 3-(4-(2,4-difluorophenoxy)-1-methyl-1H-indol-3-yl)-N-(3,4-difluorophenylsulfonyl)acrylamide::CHEMBL464414

SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(F)cc3F)cccc12

InChI Key InChIKey=PEUBYBGARVCCPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50248171   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248171(3-(4-(2,4-difluorophenoxy)-1-methyl-1H-indol-3-yl)...)
Affinity DataIC50: 18.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed