BDBM50248135 CHEMBL464411::N-(4-chlorophenylsulfonyl)-3-(1-methyl-4-(naphthalen-2-yloxy)-1H-indol-3-yl)acrylamide

SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(Cl)cc2)c2c(Oc3ccc4ccccc4c3)cccc12

InChI Key InChIKey=YHAGXNIBTRAJQS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248135   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248135(N-(4-chlorophenylsulfonyl)-3-(1-methyl-4-(naphthal...)
Affinity DataIC50: 21.9nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248135(N-(4-chlorophenylsulfonyl)-3-(1-methyl-4-(naphthal...)
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed