BDBM50247982 1-(2-((S)-3-(aminomethyl)-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)-3-methylphenyl)-N,N-dibutyl-5-methyl-1H-pyrazole-3-carboxamide::CHEMBL454406

SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1cccc(C)c1C(=O)N1Cc2ccccc2C[C@H]1CN

InChI Key InChIKey=UYNJORKAXXWQBH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50247982   

TargetApoptosis regulator Bcl-2(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50247982(1-(2-((S)-3-(aminomethyl)-1,2,3,4-tetrahydroisoqui...)
Affinity DataIC50: 175nMAssay Description:Inhibition of GST fused Bcl-2 binding to biotinylated 16 mer BH3 peptide by HTRF-LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed