BDBM50247942 CHEMBL521609::N-(3,4-difluorophenylsulfonyl)-3-(1-methyl-4-(naphthalen-2-yloxy)-1H-indol-3-yl)acrylamide

SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc4ccccc4c3)cccc12

InChI Key InChIKey=QTMBBULSCLIQGT-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50247942   

TargetProstaglandin E2 receptor EP1 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50247942(N-(3,4-difluorophenylsulfonyl)-3-(1-methyl-4-(naph...)
Affinity DataIC50: 1.42E+3nMAssay Description:Displacement of radioligand from EP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50247942(N-(3,4-difluorophenylsulfonyl)-3-(1-methyl-4-(naph...)
Affinity DataIC50: 1.25E+4nMAssay Description:Displacement of radioligand from EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50247942(N-(3,4-difluorophenylsulfonyl)-3-(1-methyl-4-(naph...)
Affinity DataIC50: 1.25E+4nMAssay Description:Displacement of radioligand from EP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50247942(N-(3,4-difluorophenylsulfonyl)-3-(1-methyl-4-(naph...)
Affinity DataIC50: 1.88E+3nMAssay Description:Displacement of radioligand from IP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50247942(N-(3,4-difluorophenylsulfonyl)-3-(1-methyl-4-(naph...)
Affinity DataIC50: 3.59E+3nMAssay Description:Displacement of radioligand from FP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50247942(N-(3,4-difluorophenylsulfonyl)-3-(1-methyl-4-(naph...)
Affinity DataIC50: 7.40nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50247942(N-(3,4-difluorophenylsulfonyl)-3-(1-methyl-4-(naph...)
Affinity DataIC50: 15.9nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed