BDBM50247728 (E)-3-(5-((Z)-4-Methyl-3-oxo-3,4-dihydrobenzo[b][1,4]oxazin-2-ylidenemethyl)thiophen-2-yl)-N-(pyridin-3-ylmethyl)acrylamide::CHEMBL461776

SMILES CN1C(=O)\C(Oc2ccccc12)=C\c1ccc(\C=C\C(=O)NCc2cccnc2)s1

InChI Key InChIKey=XZSDNYHHWDDDFV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50247728   

TargetVascular endothelial growth factor receptor 2(Human)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50247728((E)-3-(5-((Z)-4-Methyl-3-oxo-3,4-dihydrobenzo[b][1...)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of KDR expressed in baculovirus system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50247728((E)-3-(5-((Z)-4-Methyl-3-oxo-3,4-dihydrobenzo[b][1...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of ABL expressed in baculovirus system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed