BDBM50247721 4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide::CHEMBL511186

SMILES NS(=O)(=O)c1ccc(CNS(=O)(=O)c2ccc(F)cc2)cc1

InChI Key InChIKey=RXAAVLURIXEENO-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50247721   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
Forman Christian College (A Chartered University)

Curated by ChEMBL
LigandPNGBDBM50247721(4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide |...)
Affinity DataIC50: 2.94E+3nMAssay Description:Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetIntestinal-type alkaline phosphatase(Bovine)
Forman Christian College (A Chartered University)

Curated by ChEMBL
LigandPNGBDBM50247721(4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide |...)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of calf intestinal alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectrophotometric...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
Forman Christian College (A Chartered University)

Curated by ChEMBL
LigandPNGBDBM50247721(4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide |...)
Affinity DataIC50: 215nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50247721(4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide |...)
Affinity DataKi:  100nMAssay Description:Inhibition of human recombinant CA2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50247721(4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide |...)
Affinity DataKi:  290nMAssay Description:Inhibition of human recombinant CA9 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50247721(4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide |...)
Affinity DataKi:  870nMAssay Description:Inhibition of human recombinant CA1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bovine)
Forman Christian College (A Chartered University)

Curated by ChEMBL
LigandPNGBDBM50247721(4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide |...)
Affinity DataKi:  1.25E+3nMAssay Description:Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed