BDBM50247164 CHEMBL4101901

SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(s2)N2CCC3(CCc4ccccc34)CC2)cc1

InChI Key InChIKey=DRUKLGQQEASCBQ-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50247164   

TargetFree fatty acid receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50247164(CHEMBL4101901)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human GPR40 receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux after 2.5 hrs measured over 3 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50247164(CHEMBL4101901)
Affinity DataKi:  8.20nMAssay Description:Competitive displacement of [3H]-TAK-875 from full length human recombinant GPR40 expressed in HEK293 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2019
Entry Details Article
PubMed