BDBM50247136 2-(7-phenylheptanoyl)oxazole-4-carbonitrile::CHEMBL462423

SMILES O=C(CCCCCCc1ccccc1)c1nc(co1)C#N

InChI Key InChIKey=IGDLMZPDBOKHRJ-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50247136   

TargetNeutral cholesterol ester hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247136(2-(7-phenylheptanoyl)oxazole-4-carbonitrile | CHEM...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of KIAA1363More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247136(2-(7-phenylheptanoyl)oxazole-4-carbonitrile | CHEM...)
Affinity DataIC50: 30nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247136(2-(7-phenylheptanoyl)oxazole-4-carbonitrile | CHEM...)
Affinity DataIC50: 20nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50247136(2-(7-phenylheptanoyl)oxazole-4-carbonitrile | CHEM...)
Affinity DataIC50: 575nMAssay Description:Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247136(2-(7-phenylheptanoyl)oxazole-4-carbonitrile | CHEM...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed