BDBM50246528 4-amino-8-benzyl-2-(benzylthio)pteridine-6,7(5H,8H)-dione::CHEMBL462388

SMILES Nc1nc(SCc2ccccc2)nc2n(Cc3ccccc3)c(=O)c(=O)[nH]c12

InChI Key InChIKey=CCQMPJHOMKFSTQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50246528   

TargetGlutamate racemase(Enterococcus faecalis (strain ATCC 700802 / V583))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50246528(4-amino-8-benzyl-2-(benzylthio)pteridine-6,7(5H,8H...)
Affinity DataIC50: 2.10E+4nMpH: 8.0Assay Description:Inhibition of Enterococcus faecalis murI assessed as effect on conversion of D-glutamate to L-glutamate at pH 8.0 by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed