BDBM50246098 5-(5-methyl-4-(pyridin-2-ylmethylamino)pyrimidin-2-ylamino)indolin-2-one::CHEMBL471698

SMILES Cc1cnc(Nc2ccc3NC(=O)Cc3c2)nc1NCc1ccccn1

InChI Key InChIKey=MRGDFKGWULXLAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246098   

TargetFocal adhesion kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246098(5-(5-methyl-4-(pyridin-2-ylmethylamino)pyrimidin-2...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of GST-tagged FAK assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246098(5-(5-methyl-4-(pyridin-2-ylmethylamino)pyrimidin-2...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of GST-tagged pyk2 assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed