BDBM50246036 2,2,2-Trifluoro-1-[5-(3-{[(4-fluorobenzyl)sulfonyl]methyl}-1,2,4-oxadiazol-5-yl)thiophen-2-yl]ethanone::2,2,2-trifluoro-1-(5-(3-((4-fluorobenzylsulfonyl)methyl)-1,2,4-oxadiazol-5-yl)thiophen-2-yl)ethanone::CHEMBL512517

SMILES Fc1ccc(CS(=O)(=O)Cc2noc(n2)-c2ccc(s2)C(=O)C(F)(F)F)cc1

InChI Key InChIKey=YQEDPXDHNQVERX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50246036   

TargetHistone deacetylase 4(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50246036(2,2,2-Trifluoro-1-[5-(3-{[(4-fluorobenzyl)sulfonyl...)
Affinity DataIC50: 60nMAssay Description:Inhibition of His-tagged HDAC4 catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50246036(2,2,2-Trifluoro-1-[5-(3-{[(4-fluorobenzyl)sulfonyl...)
Affinity DataIC50: 700nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50246036(2,2,2-Trifluoro-1-[5-(3-{[(4-fluorobenzyl)sulfonyl...)
Affinity DataIC50: 6.55E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50246036(2,2,2-Trifluoro-1-[5-(3-{[(4-fluorobenzyl)sulfonyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50246036(2,2,2-Trifluoro-1-[5-(3-{[(4-fluorobenzyl)sulfonyl...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50246036(2,2,2-Trifluoro-1-[5-(3-{[(4-fluorobenzyl)sulfonyl...)
Affinity DataIC50: 700nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed