BDBM50245988 4-((5-(5-(2,2,2-trifluoroacetyl)thiophen-2-yl)-1,2,4-oxadiazol-3-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one::CHEMBL462203

SMILES FC(F)(F)C(=O)c1ccc(s1)-c1nc(CN2C(=O)COc3ccccc23)no1

InChI Key InChIKey=ASCINMAZWGAFOZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50245988   

TargetHistone deacetylase 4(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50245988(4-((5-(5-(2,2,2-trifluoroacetyl)thiophen-2-yl)-1,2...)
Affinity DataIC50: 15nMAssay Description:Inhibition of His-tagged HDAC4 catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50245988(4-((5-(5-(2,2,2-trifluoroacetyl)thiophen-2-yl)-1,2...)
Affinity DataIC50: 410nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50245988(4-((5-(5-(2,2,2-trifluoroacetyl)thiophen-2-yl)-1,2...)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50245988(4-((5-(5-(2,2,2-trifluoroacetyl)thiophen-2-yl)-1,2...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed