BDBM50245985 2,2,2-trifluoro-1-(5-(3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)thiophen-2-yl)ethanone::CHEMBL461333

SMILES FC(F)(F)C(=O)c1ccc(s1)-c1nc(no1)-c1ccncc1

InChI Key InChIKey=LMQNGVNXXKVSAT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50245985   

TargetHistone deacetylase 6(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50245985(2,2,2-trifluoro-1-(5-(3-(pyridin-4-yl)-1,2,4-oxadi...)
Affinity DataIC50: 570nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50245985(2,2,2-trifluoro-1-(5-(3-(pyridin-4-yl)-1,2,4-oxadi...)
Affinity DataIC50: 590nMAssay Description:Inhibition of His-tagged HDAC4 catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50245985(2,2,2-trifluoro-1-(5-(3-(pyridin-4-yl)-1,2,4-oxadi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed