BDBM50245945 2-(4-((1-allyl-5-(4-tert-butylphenyl)-1H-pyrazole-3-carboxamido)methyl)-2-methylphenoxy)-2-methylpropanoic acid::CHEMBL516964

SMILES Cc1cc(CNC(=O)c2cc(-c3ccc(cc3)C(C)(C)C)n(CC=C)n2)ccc1OC(C)(C)C(O)=O

InChI Key InChIKey=SXMPFVUTKBRPST-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50245945   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50245945(2-(4-((1-allyl-5-(4-tert-butylphenyl)-1H-pyrazole-...)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human PPARalpha receptor by cell based transient transfection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50245945(2-(4-((1-allyl-5-(4-tert-butylphenyl)-1H-pyrazole-...)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transient transfection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50245945(2-(4-((1-allyl-5-(4-tert-butylphenyl)-1H-pyrazole-...)
Affinity DataEC50:  69nMAssay Description:Agonist activity at human PPARgamma receptor by cell based transient transfection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50245945(2-(4-((1-allyl-5-(4-tert-butylphenyl)-1H-pyrazole-...)
Affinity DataEC50:  6.00E+3nMAssay Description:Agonist activity at mouse PPARalpha receptor by cell based transient transfection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50245945(2-(4-((1-allyl-5-(4-tert-butylphenyl)-1H-pyrazole-...)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at mouse PPARdelta receptor by cell based transient transfection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50245945(2-(4-((1-allyl-5-(4-tert-butylphenyl)-1H-pyrazole-...)
Affinity DataEC50:  150nMAssay Description:Agonist activity at mouse PPARgamma receptor by cell based transient transfection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed