BDBM50245875 CHEMBL4086961

SMILES CC#CCOc1cnc(cn1)C(=O)Nc1ccc(F)c(c1)[C@]1(C)CC(=O)N(C)C(N)=N1

InChI Key InChIKey=JLARKAUCJBQEDP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245875   

TargetBeta-secretase 1(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50245875(CHEMBL4086961)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of BACE-1 (unknown origin) using APP derived polypeptide harboring Lys-Met/Asn-Leu mutation as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details Article
PubMed