BDBM50245874 CHEMBL4078371

SMILES CC#Cc1cncc(c1)-c1ccc2OC[C@]3(N=C(N)C[C@@H]3C(F)(F)F)c2c1

InChI Key InChIKey=QXBFTWSGJHVMLE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245874   

TargetBeta-secretase 1(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50245874(CHEMBL4078371)
Affinity DataIC50: 115nMAssay Description:Inhibition of BACE-1 (unknown origin) using APP derived polypeptide harboring Lys-Met/Asn-Leu mutation as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details Article
PubMed