BDBM50245807 CHEMBL509373::rac-2-(aminomethyl)-1-(o-tolyloxy)-2,3-dihydro-1H-inden-2-ol

SMILES Cc1ccccc1OC1c2ccccc2CC1(O)CN

InChI Key InChIKey=LXXOMHAIVSCBSY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50245807   

TargetSodium-dependent noradrenaline transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245807(rac-2-(aminomethyl)-1-(o-tolyloxy)-2,3-dihydro-1H-...)
Affinity DataIC50: 75nMAssay Description:Inhibition of norepinephrine uptake at human NET transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245807(rac-2-(aminomethyl)-1-(o-tolyloxy)-2,3-dihydro-1H-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of serotonin uptake at human SERT transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245807(rac-2-(aminomethyl)-1-(o-tolyloxy)-2,3-dihydro-1H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine uptake at human DAT transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50245807(rac-2-(aminomethyl)-1-(o-tolyloxy)-2,3-dihydro-1H-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed