BDBM50245779 2,2,2-trifluoro-1-(5-(5-(thiophen-2-yl)-1,3,4-oxadiazol-2-yl)thiophen-2-yl)ethanone::CHEMBL454672

SMILES FC(F)(F)C(=O)c1ccc(s1)-c1nnc(o1)-c1cccs1

InChI Key InChIKey=SDZYIFVVCCKFKG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50245779   

TargetHistone deacetylase 6(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50245779(2,2,2-trifluoro-1-(5-(5-(thiophen-2-yl)-1,3,4-oxad...)
Affinity DataIC50: 160nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50245779(2,2,2-trifluoro-1-(5-(5-(thiophen-2-yl)-1,3,4-oxad...)
Affinity DataIC50: 450nMAssay Description:Inhibition of His-tagged HDAC4 catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50245779(2,2,2-trifluoro-1-(5-(5-(thiophen-2-yl)-1,3,4-oxad...)
Affinity DataIC50: 500nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50245779(2,2,2-trifluoro-1-(5-(5-(thiophen-2-yl)-1,3,4-oxad...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed