BDBM50245768 5-methyl-4-phenyl-1-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)-1H-imidazol-2(3H)-one::CHEMBL452087

SMILES Cc1c([nH]c(=O)n1C1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1)-c1ccccc1

InChI Key InChIKey=VIJNCDUDLOASFU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245768   

TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50245768(5-methyl-4-phenyl-1-(1-((1-(4-(trifluoromethyl)phe...)
Affinity DataIC50: 26nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50245768(5-methyl-4-phenyl-1-(1-((1-(4-(trifluoromethyl)phe...)
Affinity DataIC50: 71nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed