BDBM50245643 CHEMBL4081428

SMILES CCC(=O)Nc1cc(Nc2cc(cn(C)c2=O)-c2cccc(NC(=O)c3ccc(cc3)C(C)(C)C)c2C)ccc1C(=O)N1CCOCC1

InChI Key InChIKey=SENQYYGFRJAZIB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245643   

TargetTyrosine-protein kinase BTK(Human)
University of Science and Technology of China

Curated by ChEMBL
LigandPNGBDBM50245643(CHEMBL4081428)
Affinity DataIC50: 163nMAssay Description:Inhibition of full length recombinant human N-terminal His tagged BKT expressed in baculovirus infected Sf9 insect cells using poly (Glu,Tyr)4:1 as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
University of Science and Technology of China

Curated by ChEMBL
LigandPNGBDBM50245643(CHEMBL4081428)
Affinity DataEC50: >100nMAssay Description:Irreversible inhibition of recombinant full length wild-type 3'-FLAG-tagged BTK (unknown origin) expressed in HEK293T cells assessed as reduction in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed