BDBM50245588 CHEMBL4085868

SMILES CN(C)c1ccc(cc1)C(=O)Nc1cccc(c1C)-c1cc(Nc2ccc(C(=O)N3CCOCC3)c(NC(=O)C=C)c2)c(=O)n(C)c1

InChI Key InChIKey=AQBOZCORBWWYIG-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50245588   

TargetCytoplasmic tyrosine-protein kinase BMX(Human)
University of Science and Technology of China

Curated by ChEMBL
LigandPNGBDBM50245588(CHEMBL4085868)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged BMX expressed in baculovirus infected Sf9 insect cells using poly (Glu,Tyr)4:1 as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
University of Science and Technology of China

Curated by ChEMBL
LigandPNGBDBM50245588(CHEMBL4085868)
Affinity DataIC50: 2.01E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged JAK3 (781 to end residues) expressed in baculovirus infected Sf9 insect cells using poly (Glu,T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
University of Science and Technology of China

Curated by ChEMBL
LigandPNGBDBM50245588(CHEMBL4085868)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of full length recombinant human N-terminal His tagged BKT expressed in baculovirus infected Sf9 insect cells using poly (Glu,Tyr)4:1 as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Science and Technology of China

Curated by ChEMBL
LigandPNGBDBM50245588(CHEMBL4085868)
Affinity DataIC50: 5.88E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged wild-type EGFR (695 to end residues) expressed in baculovirus infected Sf9 insect cells using p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
University of Science and Technology of China

Curated by ChEMBL
LigandPNGBDBM50245588(CHEMBL4085868)
Affinity DataKi:  113nMAssay Description:Reversible inhibition of full length recombinant human N-terminal His tagged BKT expressed in baculovirus infected Sf9 insect cells using poly (Glu,T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed