BDBM50245495 9-Hydroxy-6-(3-hydroxypropyl)-4-phenylpyrrolo-[3,4-c]carbazole-1,3(2H,6H )-dione::CHEMBL470117

SMILES OCCCn1c2ccc(O)cc2c2c3C(=O)NC(=O)c3c(cc12)-c1ccccc1

InChI Key InChIKey=WEBHIXATQUSZDF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245495   

TargetSerine/threonine-protein kinase Chk1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50245495(9-Hydroxy-6-(3-hydroxypropyl)-4-phenylpyrrolo-[3,4...)
Affinity DataIC50: 59nMAssay Description:Inhibition of Chk1 kinase assessed as GST-Cdc25 phosphorylation by Western blot determinationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50245495(9-Hydroxy-6-(3-hydroxypropyl)-4-phenylpyrrolo-[3,4...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed