BDBM50245487 2-(3-chlorophenoxy)-N-(1-((1-(4-(trifluoromethoxy)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamide::CHEMBL512185

SMILES FC(F)(F)Oc1ccc(cc1)-n1ccc(CN2CCC(CC2)NC(=O)COc2cccc(Cl)c2)c1

InChI Key InChIKey=KNFCUBWPKYSSNK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50245487   

TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50245487(2-(3-chlorophenoxy)-N-(1-((1-(4-(trifluoromethoxy)...)
Affinity DataIC50: 31nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50245487(2-(3-chlorophenoxy)-N-(1-((1-(4-(trifluoromethoxy)...)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50245487(2-(3-chlorophenoxy)-N-(1-((1-(4-(trifluoromethoxy)...)
Affinity DataIC50: 490nMAssay Description:Inhibition of human ERG expressed in CHO cells by Patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed