BDBM50245431 CHEMBL472552::N-[({5-[(6,7-Dimethoxyquinolin-4-yl)-oxy]pyridin-2-yl}amino)carbonyl]benzamide

SMILES COc1cc2nccc(Oc3ccc(NC(=O)NC(=O)c4ccccc4)nc3)c2cc1OC

InChI Key InChIKey=SNBQVLOBDRCPCE-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245431   

TargetHepatocyte growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50245431(N-[({5-[(6,7-Dimethoxyquinolin-4-yl)-oxy]pyridin-2...)
Affinity DataIC50: 480nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50245431(N-[({5-[(6,7-Dimethoxyquinolin-4-yl)-oxy]pyridin-2...)
Affinity DataKi:  50nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed