BDBM50245424 4-(2-Chlorophenyl)-9-hydroxy-6-[2-(4H-1,2,4-triazol-3-ylsulfanyl)ethyl]pyrrolo[3,4-c]carbazole-1,3(2H,6H )-dione::CHEMBL513079

SMILES Oc1ccc2n(CCSc3nnc[nH]3)c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccccc1Cl

InChI Key InChIKey=DMLSEGLMTOIWBO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245424   

TargetSerine/threonine-protein kinase Chk1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50245424(4-(2-Chlorophenyl)-9-hydroxy-6-[2-(4H-1,2,4-triazo...)
Affinity DataIC50: 420nMAssay Description:Inhibition of Chk1 kinase assessed as GST-Cdc25 phosphorylation by Western blot determinationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50245424(4-(2-Chlorophenyl)-9-hydroxy-6-[2-(4H-1,2,4-triazo...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed