BDBM50245414 CHEMBL462351::N-(1-((6-chlorobenzo[d][1,3]dioxol-5-yl)methyl)piperidin-4-yl)-2-(3-chlorophenoxy)acetamide

SMILES Clc1cccc(OCC(=O)NC2CCN(Cc3cc4OCOc4cc3Cl)CC2)c1

InChI Key InChIKey=MLMQMUQOOFSKQS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245414   

TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50245414(N-(1-((6-chlorobenzo[d][1,3]dioxol-5-yl)methyl)pip...)
Affinity DataIC50: 82nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50245414(N-(1-((6-chlorobenzo[d][1,3]dioxol-5-yl)methyl)pip...)
Affinity DataIC50: 505nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed