BDBM50245396 CHEMBL4101200

SMILES N[C@@H](CCc1ccccc1)P(O)(=O)C[C@@H](CC#C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=QCPJTEUURKCRNT-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50245396   

TargetEndoplasmic reticulum aminopeptidase 1(Human)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50245396(CHEMBL4101200)
Affinity DataIC50: 43nMAssay Description:Inhibition of ERAP1 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Human)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50245396(CHEMBL4101200)
Affinity DataIC50: 2nMAssay Description:Inhibition of IRAP (unknown origin) expressed in HEK 293S GnTI(-) cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50245396(CHEMBL4101200)
Affinity DataIC50: 37nMAssay Description:Inhibition of ERAP2 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50245396(CHEMBL4101200)
Affinity DataIC50: 43nMAssay Description:Inhibition of ERAP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50245396(CHEMBL4101200)
Affinity DataIC50: 37nMAssay Description:Inhibition of ERAP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50245396(CHEMBL4101200)
Affinity DataIC50: 2nMAssay Description:Inhibition of human IRAP using L-leucine 7-amido-4-methyl coumarin substrate by microplate fluorescence reader based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50245396(CHEMBL4101200)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ERAP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50245396(CHEMBL4101200)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of human ERAP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed