BDBM50245352 1-[5-(6,7-Dimethoxy-quinolin-4-yloxy)-pyridin-2-yl]-3-(2-oxo-2-pyrrolidin-1-yl-ethyl)urea::CHEMBL462171

SMILES COc1cc2nccc(Oc3ccc(NC(=O)NCC(=O)N4CCCC4)nc3)c2cc1OC

InChI Key InChIKey=PSJWZNOEQQDVFH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245352   

TargetHepatocyte growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50245352(1-[5-(6,7-Dimethoxy-quinolin-4-yloxy)-pyridin-2-yl...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50245352(1-[5-(6,7-Dimethoxy-quinolin-4-yloxy)-pyridin-2-yl...)
Affinity DataKi:  6.40E+3nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed