BDBM50244953 CHEMBL4063500

SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(NC(=O)CCCCCCC(=O)NO)cc3)nc2n1C1CCCC1

InChI Key InChIKey=JWILUIVAYLRFIY-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50244953   

TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50244953(CHEMBL4063500)
Affinity DataIC50: 53nMAssay Description:Inhibition of recombinant human full length C-terminal 6His-tagged CaMKK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50244953(CHEMBL4063500)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FLT4 (800-end residues) expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50244953(CHEMBL4063500)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human full length C-terminal His6-tagged Aurora B//N-terminal GST-tagged INCENP (821-end residues) expressed in baculovirus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50244953(CHEMBL4063500)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged TrkA (440-end residues) expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50244953(CHEMBL4063500)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human full length C-terminal 6His-tagged Aurora-A expressed in baculovirus infected sf21 cells using kemptide substrate in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetAurora kinase C/Inner centromere protein(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50244953(CHEMBL4063500)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged Aurora-C (35-end residues)/N-terminal GST-tagged INCENP (821-end residues) expressed in baculo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50244953(CHEMBL4063500)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK4/Cyclin-D3 co-expressed in baculovirus infected sf21 cells using Rb substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetLIM domain kinase 1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50244953(CHEMBL4063500)
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged LIMK1 (285 to 638 residues) expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50244953(CHEMBL4063500)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase TAO2(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50244953(CHEMBL4063500)
Affinity DataIC50: 84nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged TAO2 expressed in sf21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50244953(CHEMBL4063500)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human full length C-terminal 6His-tagged CDK9/Cyclin-T1 co-expressed in baculovirus infected sf21 cells using PDKtide subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed