BDBM50244851 CHEMBL461765::ethyl 1-(6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yloxy)-5-nitropyrimidin-4-yl)piperidine-4-carboxylate

SMILES CCOC(=O)C1CCN(CC1)c1ncnc(Oc2cc(nn2C)C(F)(F)F)c1[N+]([O-])=O

InChI Key InChIKey=GZORJFSITDOUIP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50244851   

TargetGlucose-dependent insulinotropic receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50244851(ethyl 1-(6-(1-methyl-3-(trifluoromethyl)-1H-pyrazo...)
Affinity DataIC50: 84nMAssay Description:Inverse agonist activity at GPR119 expressed in HEK293 cells assessed as cAMP level by flash plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed