BDBM50244785 CHEMBL4069908

SMILES CCCNNC(=O)\C=C\c1ccc(OC[C@H](Cc2c[nH]c3ccccc23)NC(=O)c2ccc(OC)cc2)cc1

InChI Key InChIKey=SRCSTPATGCALRY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50244785   

TargetHistone deacetylase 1(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50244785(CHEMBL4069908)
Affinity DataIC50: 29nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus expression system using Boc-Lys(acetyl)-AMC as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50244785(CHEMBL4069908)
Affinity DataIC50: 283nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG/His-tagged HDAC2 expressed in baculovirus expression system using Boc-Lys(acetyl)-AMC as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50244785(CHEMBL4069908)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full length recombinant human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 co-expressed in baculovirus expression system usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50244785(CHEMBL4069908)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition measured after 2 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed