BDBM50244463 (2R,3S,4S,5R,6S)-2-Hydroxymethyl-6-[2-(4-methyl-benzyl)-phenoxy]-tetrahydro-pyran-3,4,5-triol::CHEMBL447016

SMILES Cc1ccc(Cc2ccccc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1

InChI Key InChIKey=PJFAFCHMHLNMSX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244463   

TargetSodium/glucose cotransporter 2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50244463((2R,3S,4S,5R,6S)-2-Hydroxymethyl-6-[2-(4-methyl-be...)
Affinity DataEC50:  8nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as intracellular accumulation of [14C]alpha-methyl glucopyranosideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50244463((2R,3S,4S,5R,6S)-2-Hydroxymethyl-6-[2-(4-methyl-be...)
Affinity DataEC50:  8nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]-alpha-methylglucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed