BDBM50244262 CHEMBL471978::ethyl 7-ethynyl-4-methyl-5-oxo-4,5-dihydroimidazo[1,5-a]quinazoline-3-carboxylate

SMILES CCOC(=O)c1ncn2c1n(C)c(=O)c1cc(ccc21)C#C

InChI Key InChIKey=QOICRVBHAUSMFA-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50244262   

LigandPNGBDBM50244262(ethyl 7-ethynyl-4-methyl-5-oxo-4,5-dihydroimidazo[...)
Affinity DataKi:  1.68nMAssay Description:Binding affinity to GABAA alpha-5-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50244262(ethyl 7-ethynyl-4-methyl-5-oxo-4,5-dihydroimidazo[...)
Affinity DataKi:  21.4nMAssay Description:Binding affinity to GABAA alpha-2-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50244262(ethyl 7-ethynyl-4-methyl-5-oxo-4,5-dihydroimidazo[...)
Affinity DataKi:  28.4nMAssay Description:Binding affinity to GABAA alpha-1-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50244262(ethyl 7-ethynyl-4-methyl-5-oxo-4,5-dihydroimidazo[...)
Affinity DataKi: >100nMAssay Description:Binding affinity to GABAA alpha-6-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50244262(ethyl 7-ethynyl-4-methyl-5-oxo-4,5-dihydroimidazo[...)
Affinity DataKi:  198nMAssay Description:Binding affinity to GABAA alpha-3-beta-3-gamma-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed