BDBM50244240 (20S)-(2E)-1-alpha-25-Dihydroxy-2-[2-(hydroxy)-ethylidene]-16-ene-22-thia-26,27-dimethyl-19,24-dinorvitamin D3::CHEMBL472510

SMILES CCC(CC)(CS[C@@H](C)C1=CC[C@@H]\2[C@@]1(CCC/C2=C\C=C3C[C@H](C(=CCO)[C@@H](C3)O)O)C)O

InChI Key InChIKey=PIRFBNFXEQEXIT-UHFFFAOYSA-N

Data  2 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244240   

TargetVitamin D3 receptor(Mouse)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50244240((20S)-(2E)-1-alpha-25-Dihydroxy-2-[2-(hydroxy)-eth...)
Affinity DataEC50:  0.0260nMAssay Description:Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVitamin D3 receptor(Mouse)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50244240((20S)-(2E)-1-alpha-25-Dihydroxy-2-[2-(hydroxy)-eth...)
Affinity DataEC50:  0.0850nMAssay Description:Increase in mouse VDR-mediated transcriptional activity in african green monkey COS7 cells after 24 hrs by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed