BDBM50243950 CHEMBL4079746

SMILES Nc1ccc(cn1)-c1ccc2ncc3ncc(=O)n(C4CCN(CC#N)CC4)c3c2c1

InChI Key InChIKey=PQEIMHBVHXTVNA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50243950   

TargetSerine/threonine-protein kinase mTOR(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50243950(CHEMBL4079746)
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant human mTOR (1362 to end residues)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50243950(CHEMBL4079746)
Affinity DataIC50: 62nMAssay Description:Inhibition of full length recombinant human ATMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50243950(CHEMBL4079746)
Affinity DataIC50: 26nMAssay Description:Inhibition of full length recombinant human DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details Article
PubMed
TargetFKBP12A/mTOR(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50243950(CHEMBL4079746)
Affinity DataIC50: 8nMAssay Description:Inhibition of full length recombinant human mTOR/FKBP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details Article
PubMed