BDBM50243942 1-(naphthalen-2-yl)-3-aza-bicyclo[3.1.0]hexane::CHEMBL452045

SMILES C1C2CNCC12c1ccc2ccccc2c1

InChI Key InChIKey=HKHCSWPSUSWGLI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243942   

TargetTransporter(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243942(1-(naphthalen-2-yl)-3-aza-bicyclo[3.1.0]hexane | C...)
Affinity DataIC50: 36nMAssay Description:Inhibition of norepinephrine uptake at NET in rat brain synaptosomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243942(1-(naphthalen-2-yl)-3-aza-bicyclo[3.1.0]hexane | C...)
Affinity DataIC50: 50nMAssay Description:Inhibition of serotonin uptake at SERT in rat brain synaptosomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243942(1-(naphthalen-2-yl)-3-aza-bicyclo[3.1.0]hexane | C...)
Affinity DataIC50: 190nMAssay Description:Inhibition of dopamine uptake at cloned DAT in rat brain synaptosomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed