BDBM50243912 2-(4-hydroxybenzyl)-N,N-diethyl-1-isopentyl-1H-benzo[d]imidazole-5-carboxamide::CHEMBL486438

SMILES CCN(CC)C(=O)c1ccc2n(CCC(C)C)c(Cc3ccc(O)cc3)nc2c1

InChI Key InChIKey=KWGUVZUNTGXISE-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50243912   

TargetCholinesterase(Human)
Julius Maximilian University Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50243912(2-(4-hydroxybenzyl)-N,N-diethyl-1-isopentyl-1H-ben...)
Affinity DataIC50: 2.50E+4nMAssay Description:Pseudo-irreversible inhibition of human BChE using butyrylthiocholine iodide as substrate incubated for 20 mins followed by substrate addition by Ell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
Julius Maximilian University Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50243912(2-(4-hydroxybenzyl)-N,N-diethyl-1-isopentyl-1H-ben...)
Affinity DataIC50: 2.21E+3nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cell membrane incubated for 3 hrs by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
Julius Maximilian University Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50243912(2-(4-hydroxybenzyl)-N,N-diethyl-1-isopentyl-1H-ben...)
Affinity DataKi:  799nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50243912(2-(4-hydroxybenzyl)-N,N-diethyl-1-isopentyl-1H-ben...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed